Activation of the conserved Hippo kinases by inflammasome-brought on proteolytic cleavage controls programmed cell loss of life in macrophages
Court docket cases of the National Academy of Sciences, Volume 122, Difficulty 5, February 2025.
SignificanceThe Hippo pathway is extremely conserved in eukaryotes from yeasts to humans. Whereas folks with mutations in the Hippo kinase geneMST1experience recurrent infection, minute is known about the role of MST1 and its homolog MST2 in innate …
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